T-cell lymphomas in a tertiary care center of Mangalore

Background: The clinicomorphology and immunohistochemical features of T-cell lymphomas have been documented. Aim: The aim of the study was to evaluate the spectrum of clincopathological features of T-cell lymphoma with immunohistochemistry correlation in a tertiary care center. Materials and Methods: The present study was conducted on 19 biopsy specimens received from the Department of Pathology, Kasturba Medical College, from referral hospitals of Mangalore city. Cases of nodal and extranodal T-cell lymphomas diagnosed between January 2012 and December 2015 were selected with evaluation of clinical data, histomorphological features, and immunophenotyping. Appropriate panel of antibodies was chosen after morphological evaluation of the cases. Results: Of the 19 cases of T-cell lymphomas, 14 were nodal disease and 5 were extranodal disease. Among the nodal lymphomas, five were primary peripheral T-cell lymphoma-not otherwise specified (PTCL-NOS), four were cases of lymphoblastic lymphoma, three were cases of angioimmunoblastic T-cell lymphomas, and two were cases of anaplastic large-cell lymphoma anaplastic lymphoma kinase (ALK) negative. In extranodal disease, two were mycosis fungoides of skin, one case each of subcutaneous panniculitis-like T-cell lymphoma, T-cell lymphoblastic lymphoma of tonsil, and T-cell lymphoma of the stomach. Conclusions: The diagnosis and subclassification of PTCLs is necessary for therapeutic and prognostic purposes

Urinary Schistosomiasis Detected by Chance in India : A Case Report.

Schistosomiasis is a parasitic trematode that is lesscommonly seen in India. The clinical manifestationsrange from acute, sub acute and chronic phases. Agranulomatous type of lesion formed by Schistosomahematobium in the lower urinary tract. We present acase of rare neglected tropical infection in this part ofDakshin Kannada. A 66-year-old man presents withhistory of irritative voiding symptoms, urgency,incontinence, and nocturia of 2 months duration. CTUrogram showed bladder wall thickening. Cystoscopyshowed granuloma in the posterolateral wall of thebladder. Urine microscopy picked up Schistosomahematobium eggs. Bladder biopsy showed chronicinflammatory type of lesion. This is a case of confirmedchronic granulomatous urinary schistosomiasis in anon-endemic region, and successfully treated.Clinicians should become aware of the existence of thisparasite in few pockets in India.

Second primary lung cancer with tuberculosis.

We report a rare case of second primary lung cancer presenting metachronoulsy in a patient with laryngeal cancer. Though regional recurrence and second primary neoplasm of the upper aerodigestive tract are common following laryngeal cancers, second primary cancers of the lung are uncommon. Adding to the rarity of the case was the presence of concurrent active pulmonary tuberculosis with second primary neoplasm of the lung.

Primary primitive neuroectodermal tumor of the ovary: a case report.

Ovarian germ cell tumours having neuroectodermal cells, growing in patterns reminiscent of tumours of the central nervous system are rare. We report a case of primary primitive neuroectodermal tumor(PNET) of the ovary detected soon after pregnancy.